dc.contributor.advisor | Llaque Sánchez, María Rocío Del Pilar | |
dc.contributor.advisor | Polo Gamboa, Jaime Abelardo | |
dc.contributor.author | Mendoza Rodríguez, María Del Pilar | |
dc.date.accessioned | 2019-03-21T22:28:12Z | |
dc.date.available | 2019-03-21T22:28:12Z | |
dc.date.issued | 2019 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12692/29993 | |
dc.description.abstract | El objetivo principal de la presente investigación fue evaluar el efecto antibacteriano del aceite
esencial del Piper aduncum “matico” comparado con oxacilina 1 ug sobre Staphylococcus aureus
ATCC 25923. Se realizaron cuatro diluciones (100%,75%,50% y 25%) y un control neutro con DMSO.
Se obtuvo que el aceite esencial de Piper aduncum mostró halos de inhibición a partir de la dilución
de 75% con 13.70 mm (DS.0.919+0.3 IC 95%(13.14-14.3)), al 100% el halo de inhibición fue de 16.50
mm (DS: 1.609+ 0.477. IC 95% (15.52- 17.48)); valores considerados como eficaces en relación al
patrón CSI (>12mm), sin embargo, no supera el halo de inhibición del medicamento oxacilina con
30.60 mm (DS: 1.080+0342. IC 95%(30.7-31.2)). A las concentraciones de 50% y 25% no se observó
efecto antibacteriano. El análisis estadístico ANOVA fue altamente significativo donde se obtuvo un
valor de p<0.01, al igual que la prueba de Tukey demostró que los grupos evaluados eran
homogéneos y el grupo con mayor halo de inhibición fue para oxacilina seguido del aceite esencial
al 100% de la planta en estudio evidenciándose que a mayor concentración el halo de inhibición
aumentaba. Se concluye que el aceite esencial del Piper aduncum si tiene efecto antibacteriano
sobre Staphylococcus aureus pero no superando el halo de inhibición de la oxacilina. | es_PE |
dc.description.abstract | The principal objective of this research was to evaluate the antibacterial effect of the essential oil of Piper aduncum "matico" compared with oxacillin 1 ug on Staphylococcus aureus ATCC 25923. Four dilutions (100%, 75%, 50% and 25%) and a neutral control with DMSO were performed. It was found that Piper aduncum essential oil showed zones of inhibition at 75% dilution with 13.70 mm (SD.0.919+0.3 CI 95% (13.14-14.3)), at 100% the zone of inhibition was 16.50 mm (SD: 1.609+ 0.477. CI 95% (15.52- 17.48)); values considered effective in relation to the CSI standard (>12mm), however, it does not exceed the zone of inhibition of the drug oxacillin with 30.60 mm (SD: 1.080+0342. CI 95 %(30.7-31.2)). At concentrations of 50% and 25% no antibacterial effect was observed. ANOVA statistical analysis was highly significant with a value of p<0.01, and Tuke-test showed that the evaluated groups were homogeneous and the group with greater zone of inhibition was for oxacillin, followed by the essential oil at 100% concentration of the plant under study, showing that the greater the concentration, the greater the zone of inhibition. It is concluded that the essential oil of Piper aduncum does have an antibacterial effect on Staphylococcus aureus but it does not exceed the zone of inhibition of oxacillin. | es_PE |
dc.description.uri | Tesis | es_PE |
dc.format | application/pdf | es_PE |
dc.language.iso | spa | es_PE |
dc.publisher | Universidad César Vallejo | es_PE |
dc.rights | info:eu-repo/semantics/embargoedAccess | es_PE |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | es_PE |
dc.source | Universidad César Vallejo | es_PE |
dc.source | Repositorio Institucional - UCV | es_PE |
dc.subject | Piper aduncum | es_PE |
dc.subject | eficacia | es_PE |
dc.subject | halo | es_PE |
dc.subject | aceite esencial | es_PE |
dc.subject | matico | es_PE |
dc.subject | Stapylococcus aureus | es_PE |
dc.subject | efecto antibacteriano | es_PE |
dc.subject | efficacy | es_PE |
dc.subject | zone of inhibition | es_PE |
dc.subject | essential oil, matico | es_PE |
dc.subject | antibacterial effect | es_PE |
dc.title | Efecto antibacteriano del aceite esencial de piper aduncum “matico” sobre staphylococcus aureus atcc 25923 comparado con oxacilina, estudio invitro | es_PE |
dc.type | info:eu-repo/semantics/bachelorThesis | es_PE |
thesis.degree.discipline | Medicina | es_PE |
thesis.degree.grantor | Universidad César Vallejo. Facultad de Ciencias de la Salud | es_PE |
thesis.degree.name | Médico Cirujano | es_PE |
dc.description.sede | Trujillo | es_PE |
dc.description.escuela | Escuela de Medicina | es_PE |
dc.description.lineadeinvestigacion | Enfermedades Infecciosas y Tropicales | es_PE |
renati.discipline | 912016 | es_PE |
renati.level | https://purl.org/pe-repo/renati/level#tituloProfesional | es_PE |
renati.type | https://purl.org/pe-repo/renati/type#tesis | es_PE |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.01.00 | es_PE |
dc.publisher.country | PE | es_PE |