Mostrar el registro sencillo del ítem
Therapeutic abandonment in multidrug-resistant tuberculosis: Associated factors in a high burden region in Perú
dc.contributor.author | Rivera, Orianda | |
dc.contributor.author | Benites, Santiago | |
dc.contributor.author | Mendigure, Julio | |
dc.contributor.author | Bonilla, César Antonio | |
dc.date.accessioned | 2019-05-10T04:35:57Z | |
dc.date.available | 2019-05-10T04:35:57Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Rivera, O., Benites, S., Mendigure, J., & Bonilla, C. A. (2019). Therapeutic abandonment in multidrug-resistant tuberculosis: Associated factors in a high burden region in Perú . Biomedica, 39, 1–31. Retrieved from https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063998791&partnerID=40&md5=7cf49f2b153b87b4d61ab44fc1045fd9 | es_PE |
dc.identifier.issn | 01204157 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12692/32533 | |
dc.description.abstract | Introduction: In the approach of multidrug-resistant tuberculosis, the therapeutic abandonment constitutes a serious problem of public health, affecting the quality of life of patients, families and community. Addressing it poses a burden on health systems, because it causes free sources of transmission in the community, and increases in prevalence and mortality. Hence the need to investigate those factors associated with this situation. Objective: To identify risk factors associated with treatment default in patients with multidrug-resistant tuberculosis in the Callao-Peru region. Materials and methods: Analytical case-control study (cases = 80 and controls = 180) that started treatment from January 01, 2010 to December 31, 2012. The factors were identified by logistic regression, calculating the odds ratios (OR) and 95% confidence intervals. Results: Finding risk factors in the multivariate analysis: Not having knowledge of the disease, OR aj = 23.10 [95% CI, 3.6-36.79; (p .002)], Do not believe in healing, OR aj = 117.34 [95% CI 13.57-124.6; (p .000)]; Not having social support, OR aj = 19.16 [95% CI 1.32-27.77; (p .030)]; Do not consider adequate working hours, OR aj = 78.13 [IC95% 4.84-125.97; (p .002)]; Do not receive laboratory reports, OR aj = 46.13 [95% CI 2.85-74.77; (p .007)] Conclusions: Health services should direct efforts for the early identification of conditions that could become risk factors, which would help preventively implement effective, rapid and high-impact interventions. © 2019 Instituto Nacional de Salud. | es_PE |
dc.description.abstract | Introducción. En el abordaje de la tuberculosis multidrogorresistente, el abandono terapéutico, constituye grave problema de salud pública, afectando la calidad de vida de pacientes, familias y comunidad. El enfrentarlo, supone una carga para los sistemas sanitarios, debido a que provoca fuentes de transmisión libres en la comunidad, e incremento de prevalencia y mortalidad. De ahí la necesidad de investigar aquellos factores asociados a esta situación. Objetivo. Identificar factores de riesgo asociados al abandono del tratamiento en pacientes con tuberculosis multidrogorresistente en la Region Callao-Perú. Materiales y métodos. Estudio analítico de casos y controles (casos=80 y controles=180) que iniciaron tratamiento del 01 enero 2010 al 31 diciembre 2012. Los factores se identificaron mediante regresión logística, calculándose las odds ratios (OR) e intervalos de confianza al 95% (IC). Resultados. En el análisis multivariado, se identificaron los factores de riesgo: no tener conocimiento de la enfermedad, OR aj= 23.10 [IC95% 3.6-36.79; (p .002)], no creer en curación, OR aj= 117.34 [IC95% 13.57-124.6; (p .000)]; no tener apoyo social, OR aj= 19.16 [IC95% 1.32-27.77; (p .030)]; no considerar adecuado el horario de atención, OR aj= 78.13 [IC95% 4.84-125.97; (p .002)]; y no recibir informes de laboratorio, OR aj= 46.13 [IC95% 2.85-74.77; (p .007)]. Conclusión. Los servicios de salud, deben direccionar esfuerzos para la identificación precoz de condiciones que podrían convertirse en factores de riesgo, lo cual ayudaría a implementar preventivamente intervenciones efectivas, rápidas y de alto impacto. | es_PE |
dc.format | application/pdf | es_PE |
dc.language.iso | spa | es_PE |
dc.publisher | Instituto Nacional de Salud | es_PE |
dc.relation.uri | https://www.revistabiomedica.org/index.php/biomedica/article/view/4564/4167 | es_PE |
dc.rights | info:eu-repo/semantics/openAccess | es_PE |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/4.0/ | es_PE |
dc.source | Universidad César Vallejo | es_PE |
dc.subject | Drug resistance | es_PE |
dc.subject | Factores de riesgo | es_PE |
dc.subject | Resistencia a medicamentos | es_PE |
dc.subject | Risk factor | es_PE |
dc.subject | Tuberculosis | es_PE |
dc.title | Therapeutic abandonment in multidrug-resistant tuberculosis: Associated factors in a high burden region in Perú | es_PE |
dc.title.alternative | Abandono terapéutico en tuberculosis multidrogorresistente: factores asociados en una región de alta carga en Perú | es_PE |
dc.type | info:eu-repo/semantics/article | es_PE |
thesis.degree.grantor | Universidad César Vallejo. Escuela de Posgrado | es_PE |
dc.description.sede | Lima Norte | es_PE |
dc.description.peerreview | Revisión por pares | es_PE |
dc.contributor.email | bonasal@gmail.com | es_PE |
dc.identifier.journal | Biomedica | es_PE |
dc.source.volume | 39 | es_PE |
dc.source.beginpage | 1-3 | es_PE |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#5.00.00 | es_PE |
dc.relation.isPartOf | urn:issn:0120-4157 | es_PE |